ZDHHC12 REGULATES TUMOR PROPERTIES THROUGH YAP1 IN GLIOBLASTOMA

ZDHHC12 regulates tumor properties through YAP1 in glioblastoma

Background and purpose: Glioblastoma (GBM) is one of the most malignant brain tumors, however, the pathogenesis of GBM has not been thoroughly studied.The purpose of this study was to analyze the regulation of Yes-associated protein 1 (YAP1) by zinc finger DHHC domain-containing protein 12 (ZDHHC12), and the regulation of GBM tumor characteristics

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A single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution

Abstract Frozen shoulder is a spontaneously self-resolving chronic inflammatory fibrotic human disease, which distinguishes the condition from most fibrotic diseases that are progressive and irreversible.Using single-cell analysis, we identify pro-inflammatory MERTKlowCD48+ macrophages and MERTK + LYVE1 + MRC1+ macrophages enriched for negative reg

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The Combined Effect of Safety Specific Transformational Leadership and Safety Consciousness on Psychological Well-Being of Healthcare Workers

Occupational health researchers have begun to realize that the psychological well-being of healthcare workers who are providing treatment against COVID-19 is deteriorating.However, there is minimal research conducted on it, particularly in the context of leadership.The current study aims to fill this important gap by identifying critical factors th

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